Targeting Oral Cancer

This book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerginThis comprehensive study guide provides an essential framework for reviewing the core material covered by the American Board of Endodontics (ABE) examinations and understanding how best to prepare for them. With a focus toward clinical applications, the key topics of endodontics are covered in full, and the complex subjects of trauma and resorption are addressed in separate chapters with diagnosis and treatment protocols particular to these entities. To underscore the format of the ABE Oral Examination, the authors have divided each chapter into the sections used in the examination-basic sciences, medicine, diagnosis, treatment protocols, prognosis, and complications. In addition, this book provides a comprehensive review of the scientific literature. Frequent references to peer-reviewed journal articles and endodontics textbooks also guide readers for further study and focus.g role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation.